Bai Bei
Article · GlycoShiftGynura divaricata: the Chinese leaf tea, explainedComing soonThe science
Don't take our word for it. Check it.
The lab certificates we hold, every study behind our ingredients with what it did and didn't show, and plain-English guides. Last reviewed 28 October 2026.
Certificates
The lab paperwork, batch by batch.
Ask and we'll send the PDF: info@brittica.co.uk.
Ca-AKG+ · finished productBatch 2026050201All 9 ingredients within specification; heavy metals and microbiology tested.On request
GlycoShift · Gynura divaricata extract 30:1Batch HBR20260518 · certificate of analysisLead ≤2 ppm, arsenic ≤2 ppm, cadmium ≤0.2 ppm, mercury ≤0.1 ppm: conforms. E. coli, Salmonella, Staphylococcus: negative.On request
GlycoShift · botanical safetyPyrrolizidine alkaloid safety statement, July 2026Supplier declaration: cultivated, species-authenticated Gynura grown under GACP with weed-control protocols.On request
All formulasFinished-product lab testsNew tests requested for GlycoShift and Supple X; published here when received.Requested
Study library
The studies, with their limits.
These studies tested individual ingredients, not our finished formulas. Each row says what the study was and what it found, including the animal studies and the small ones.
| Ingredient | Study | What it found | Type |
|---|---|---|---|
| Gynura divaricata (Bai Bei San Qi) GlycoShift | Nutrition & Metabolism, 2018 | Less islet-cell death and more insulin-producing cells in diabetic mice | Animal |
| Mangiferin (mango leaf) GlycoShift | Int J Mol Med, 2018 | Beta-cell division and islet regeneration, even in aged mice | Animal |
| Mangiferin GlycoShift | Scientific Reports, 2015 | 150 mg a day: insulin resistance −8%, triglycerides −14% in 12 weeks | Human RCT |
| Puerarin (Ge Gen, kudzu root) GlycoShift | Frontiers in Pharmacology, 2022 | Beta-cell replication and new beta cells via the GLP-1 receptor | Review |
| Berberine (phytosome in GlycoShift) GlycoShift | Frontiers in Pharmacology, 2024 | 50 trials, 4,150 people: lower after-meal glucose, LDL and triglycerides | Meta-analysis |
| Herbs and beta cells GlycoShift | Evid-Based Compl Alt Med, 2021 | Review of plants that support beta-cell function and regeneration, including salidroside | Review |
| Olive leaf extract (oleuropein) GlycoShift | PLoS ONE, 2013 | 46 overweight men, 12 weeks (51 mg oleuropein a day): insulin sensitivity +15% and beta-cell secretory capacity +28% vs placebo | Human RCT |
| Rhodiola rosea (salidroside) GlycoShift | Molecules, 2022 | Review of about 30 human studies on Rhodiola preparations, stress and fatigue; much of the mechanism evidence is still preclinical | Review |
| Alpha lipoic acid (R-ALA in GlycoShift) GlycoShift | Metabolism, 2018 | Randomised trials in adults with metabolic conditions: effects on fasting glucose, insulin and HbA1c; most trials used standard ALA rather than the R-form | Meta-analysis |
| Ca-AKG (calcium alpha-ketoglutarate) Ca-AKG+ | Aging, 2021 | DNA-methylation age −8 years over about 7 months in 42 users; no placebo group | Human, uncontrolled |
| Spermidine (wheat germ) Ca-AKG+ | Pekar et al., 2021 | 3.3 mg a day improved memory scores in 85 older adults over 3 months | Human RCT |
| French pine bark (PCOs) Ca-AKG+ | Cochrane Review, 2020 | Randomised trials across chronic conditions: the evidence was too uncertain to confirm a benefit for most conditions studied | Systematic review |
| Magnesium glycinate Ca-AKG+ | JPEN, 1994 | 12 patients with impaired gut absorption: magnesium bisglycinate was absorbed at least as well as magnesium oxide and was gentler on the gut | Human RCT |
| Coenzyme Q10 · ubiquinol Ca-AKG+ | Food & Function, 2018 | 10 older men, 200 mg a day for 2 weeks: ubiquinol raised plasma CoQ10 significantly; ubiquinone did not | Human RCT |
| UC-II (undenatured type 2 collagen) Supple X | Nutrition Journal, 2016 | 40 mg beat placebo and glucosamine + chondroitin over 6 months (186 people) | Human RCT |
| Boswellia serrata (AKBA) Supple X | Meta-analysis, 2020 | 9 trials, 712 people: less pain and stiffness, better function | Meta-analysis |
| Eggshell membrane Supple X | Clinical Interventions in Aging, 2018 | Faster stiffness recovery by day 4 after exercise | Human RCT |
| PEA (palmitoylethanolamide) Supple X | Nutrients, 2023 | 11 double-blind trials, 774 patients with chronic pain: lower pain scores than comparators | Meta-analysis |
| Eucommia ulmoides bark Supple X | Alternative Medicine Review, 2011 | Standardised bark extract in healthy adults: well tolerated; blood pressure −7.5/−3.9 mmHg at the higher dose over 2 weeks, no change at the lower dose over 8 weeks | Human trial |
| Centella asiatica (gotu kola) Supple X | Evid-Based Compl Alt Med, 2013 | Randomised trials in chronic venous insufficiency: improvements in circulation measures and symptoms; trial quality was limited | Systematic review |
| Grape seed extract (PCOs) Supple X | Medicine, 2016 | 16 trials, 810 people: blood pressure −6.1/−2.8 mmHg vs placebo; results varied between trials | Meta-analysis |
Articles
Plain-English guides.
HCl
Article · GlycoShiftBerberine phytosome vs berberine HCl: what the label tells youReadGP
Article · GlycoShiftBerberine side effects and medicine interactions: check these firstReadUK
Article · GlycoShiftWhere to buy berberine in the UK: a 7-point quality checklistReadGe Gen
Article · GlycoShiftGe Gen (Pueraria) in traditional Chinese useComing soonQ10
Article · Ca-AKG+Ubiquinol vs CoQ10: what's the difference?Coming soonAKG
Article · Ca-AKG+Ca-AKG and biological age: what one small study did and didn't showComing soonK2
Article · Ca-AKG+Vitamin D3 and K2: why they are pairedComing soonUC-II
Article · Supple XUC-II explained: why the amount is 40 mg, not 1,500Coming soonPEA
Article · Supple XPEA: the fatty compound your body already makesComing soonActive
Article · Supple XStaying active through menopause: what changesComing soonThe Brittica letter